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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TAF8
All Species:
7.58
Human Site:
T249
Identified Species:
13.89
UniProt:
Q7Z7C8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.67
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z7C8
NP_612639.2
310
34262
T249
S
S
E
Q
D
E
Q
T
D
T
E
N
L
A
L
Chimpanzee
Pan troglodytes
XP_001174322
174
18597
S114
L
P
A
Y
A
K
R
S
Q
R
M
V
I
T
A
Rhesus Macaque
Macaca mulatta
XP_001085409
247
27836
D187
S
E
Q
D
E
Q
T
D
T
E
N
L
A
L
H
Dog
Lupus familis
XP_538919
373
41175
T312
S
S
E
Q
D
E
Q
T
D
T
E
N
L
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQH4
308
33969
D248
S
E
Q
E
E
Q
T
D
T
E
N
N
A
L
H
Rat
Rattus norvegicus
NP_001101667
308
34098
D248
S
E
Q
D
E
Q
T
D
T
E
N
I
A
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518012
296
32759
D235
E
T
D
S
S
E
Q
D
D
Q
T
D
T
E
N
Chicken
Gallus gallus
Q5ZMS1
244
27492
D184
T
D
S
S
E
Q
D
D
Q
T
D
T
E
N
L
Frog
Xenopus laevis
Q7ZYA2
293
32715
S233
Q
V
D
E
T
D
S
S
E
Q
D
D
Q
T
D
Zebra Danio
Brachydanio rerio
Q6P0T2
308
33894
D248
E
T
D
S
S
E
Q
D
D
Q
M
D
N
D
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VWY6
328
36631
M250
G
D
S
E
N
E
E
M
D
G
D
K
S
K
E
Honey Bee
Apis mellifera
XP_395210
291
32975
E231
I
K
K
K
K
E
Q
E
T
E
E
S
E
E
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797171
285
31726
E225
P
E
E
N
Q
T
L
E
G
D
M
K
S
A
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.1
79.6
81.7
N.A.
94.5
95.4
N.A.
80.3
74.1
80
74.1
N.A.
37.5
38.3
N.A.
37.1
Protein Similarity:
100
55.8
79.6
82.3
N.A.
97
97.4
N.A.
86.1
76.4
86.7
85.1
N.A.
54.8
56.7
N.A.
56.4
P-Site Identity:
100
0
6.6
93.3
N.A.
13.3
6.6
N.A.
20
13.3
0
20
N.A.
13.3
20
N.A.
13.3
P-Site Similarity:
100
26.6
26.6
93.3
N.A.
40
26.6
N.A.
40
40
46.6
40
N.A.
40
40
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
0
0
0
0
0
0
24
16
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
24
16
16
8
8
47
39
8
24
24
0
8
16
% D
% Glu:
16
31
24
24
31
47
8
16
8
31
24
0
16
16
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
8
8
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
24
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% I
% Lys:
0
8
8
8
8
8
0
0
0
0
0
16
0
8
0
% K
% Leu:
8
0
0
0
0
0
8
0
0
0
0
8
16
24
24
% L
% Met:
0
0
0
0
0
0
0
8
0
0
24
0
0
0
0
% M
% Asn:
0
0
0
8
8
0
0
0
0
0
24
24
8
8
16
% N
% Pro:
8
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
8
0
24
16
8
31
39
0
16
24
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% R
% Ser:
39
16
16
24
16
0
8
16
0
0
0
8
16
0
0
% S
% Thr:
8
16
0
0
8
8
24
16
31
24
8
8
8
16
0
% T
% Val:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _